NBS0257 Human TGF-β1 (TGF-Beta 1/TGFB1) Protein, Tag Free, Recombinant

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Human TGF-β1 (TGF-Beta 1/TGFB1) Protein, Tag Free, Recombinant
货号:NBS0257-10μg;
NBS0257-50μg;
品牌:NoninBio

 

Human TGF-β1 (TGF-Beta 1/TGFB1) Protein, Tag Free, Recombinant

 

产品编号

产品名称

包装规格

价格

NBS0257-10μg

Human TGF-β1 (TGF-Beta 1/TGFB1) Protein, Tag Free, Recombinant

10μg

968

NBS0257-50μg

Human TGF-β1 (TGF-Beta 1/TGFB1) Protein, Tag Free, Recombinant

50μg

4360

 

产品简介:

Transforming growth factor beta 1 ( TGFB1) is also known as TGF-β1, CED, DPD1, TGFB. is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The TGFB1 protein helps control the growth and division (proliferation) of cells, the process by which cells mature to carry out specific functions (differentiation), cell movement (motility), and the self-destruction of cells (apoptosis). The TGFB1 protein is found throughout the body and plays a role in development before birth, the formation of blood vessels, the regulation of muscle tissue and body fat development, wound healing, and immune system function. TGFB1 is particularly abundant in tissues that make up the skeleton, where it helps regulate bone growth, and in the intricate lattice that forms in the spaces between cells (the extracellular matrix). Within cells, this protein is turned off (inactive) until it receives a chemical signal to become active. TGFB1 plays an important role in controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages. Most immune cells (or leukocytes) secrete TGFB1. TGFB1 has been shown to interact with TGF beta receptor 1, LTBP1, YWHAE, EIF3I and Decorin.

 

产品性质:

生物活性

Human TGF-Beta 1 Protein, Tag Free (Cat. No. TG1-H4212) inhibits the Human IL-4, premium grade (Cat. No. IL4-H4218) dependent proliferation the TF-1 cells. The specific activity of Human TGF-Beta 1 Protein, Tag Free is > 8.00ⅹ10^6 IU/mg, which is calibrated against transforming growth factor β1 (NIBSC code: 89/514) (QC tested).

产品别名

CEDLAP, TGF-beta 1, TGFB1, DPD1, TGF-beta-1, TGFB

表达系统

Human TGF-Beta 1 Protein, Tag Free (TG1-H4212) is expressed from human 293 cells (HEK293). It contains AA Ala 279 - Ser 390 (Accession # P01137-1).
Predicted N-terminus: Ala 279

分子量

The protein has a calculated MW of 12.8 kDa (monomer). The protein migrates as 14 kDa (monomer) under reducing (R) condition, and 25 kDa (Dimer) when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE).

内毒素

Less than 0.1 EU per μg by the LAL method / rFC method.

宿主蛋白残留

<0.5 ng/µg of protein tested by ELISA.

宿主核酸残留

<0.02 ng/μg of protein tested by qPCR.

纯度

>95% as determined by SDS-PAGE.

缓冲液

Lyophilized from 0.22μm filtered solution in 0.085% TFA in 30% ACN with trehalose as protectant.

外观

Lyophilized Powder

复溶方法

recommend you to follow the reconstitution protocol provided in the CoA.

 

保存条件: 

冻干粉-20℃ ~ -80℃保存,1年有效;复溶后,无菌条件下,-85℃ ~ -65℃保存,6个月有效。避免反复冻融,并将产品分装储存。

 

注意事项:

1.      为了您的安全和健康,请穿实验服并戴一次性手套操作。

 

 

 

本产品仅用于生命科学研究,不得用于医学诊断及其他用途!