产品介绍

bioGenous™  人气管类器官（分化型）培养试剂盒是一种专为分化人气道干细胞来源的人气道类器官（hAOs）而设计的无血清培养基。在分化条件下培养 10–14 天后，气道类器官可形成清晰的管腔结构，显微镜下可观察到明显的纤毛搏动或分泌物积聚现象。分化的 hAOs 展现出成熟气道上皮的关键结构与功能特征，包括：运动纤毛中高水平表达微管蛋白（tubulin），以及黏液分泌型杯状细胞中高表达 MUC5AC。结合 bioGenous™  人气管类器官（扩增型）培养试剂盒使用，该分化体系可在体外高效、稳定地重建气道上皮，广泛支持呼吸系统研究、毒理学评估、药物研发及再生医学等多领域应用。

Product Description

bioGenous™ Human Airway (Differentiation) Organoid Kit is a serum-free culture medium designed for the differentiation of human airway organoids (hAOs) derived from human airway stem cells. When cultured in differentiation conditions for 10-14 days, airway organoids develop well-defined luminal structures, within which extensive ciliary beating or accumulation of secretory material can be observed under the microscope. Differentiated hAOs exhibit key functional and structural features of the mature airway epithelium, including high expression of tubulin in motile cilia and MUC5AC in mucus-secreting goblet cells. In combination with bioGenous™ Human Airway (Expansion) Organoid Kit, this differentiation system enables robust and reproducible generation of airway epithelium in vitro, supporting a wide range of applications in respiratory research, toxicology, drug discovery, and regenerative medicine.